New Gene Discovery Could Halt Metastatic Cancer Spread
Metastatic cancer cells, which cause 90% of cancer-related deaths, must overcome numerous hurdles to spread from a primary tumor through the bloodstream and re-establish themselves in different tissues.
A new study led by investigators from the Mass General Cancer Center has identified a gene whose expression confers a growth advantage to these cells.
Expression of Gstt1 enables the cells to change the surrounding environment to support their growth. The findings could lead to new strategies to treat metastatic cancer and would be particularly impactful for patients with pancreatic cancer.
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